Successful TRPV1 antagonist treatment for cardiac hypertrophy and heart failure in mice

34Citations
Citations of this article
43Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

Heart failure is becoming a global epidemic. It exerts a staggering toll on quality of life, and substantial medical and economic impact. In a pre-clinical model of cardiac hypertrophy and heart failure, we were able to overcome loss of heart function by administering the TRPV1 antagonist BCTC (4-(3-Chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-1- piperazinecarboxamide). The results presented here identify TRPV1 antagonists as new treatment options for cardiac hypertrophy and heart failure.

Cite

CITATION STYLE

APA

Horton, J. S., Buckley, C. L., & Stokes, A. S. (2013). Successful TRPV1 antagonist treatment for cardiac hypertrophy and heart failure in mice. Channels, 7(1). https://doi.org/10.4161/chan.23006

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free