Total synthesis of capsanthin using Lewis acid-promoted regio- and stereoselective rearrangement of tetrasubstituted epoxide

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Abstract

The synthesis of capsanthin 1 was accomplished via the C15-cyclopentyl ketone 13 prepared by Lewis acid-promoted regio-and stereoselective rearrangement of the epoxide 12.

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Yamano, Y., & Ito, M. (2001). Total synthesis of capsanthin using Lewis acid-promoted regio- and stereoselective rearrangement of tetrasubstituted epoxide. Chemical and Pharmaceutical Bulletin, 49(12), 1662–1663. https://doi.org/10.1248/cpb.49.1662

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