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1-arylsulfonyl-2-(Pyridylmethylsulfinyl) benzimidazoles as new proton pump inhibitor prodrugs

Molecules (2009) 14(12) 5247-5280
DOI: 10.3390/molecules14125247
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Abstract

New arylsulfonyl proton pump inhibitor (PPI) prodrug forms were synthesized. These prodrugs provided longer residence time of an effective PPI plasma concentration, resulting in better gastric acid inhibition.

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Shin, J. M., Sachs, G., Cho, Y. M., & Garst, M. (2009). 1-arylsulfonyl-2-(Pyridylmethylsulfinyl) benzimidazoles as new proton pump inhibitor prodrugs. Molecules, 14(12), 5247–5280. https://doi.org/10.3390/molecules14125247

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