Abstract
Migratory cells translocate membrane type-1 matrix metalloproteinase (MT1-MMP) to podosomes or invadosomes to break extracellular matrix barriers. In this issue, El Azzouzi et al. (2016. J. Cell. Biol. http ://dx .doi .org /10 .1083 /jcb .201510043) describe an unexpected function for the MT1-MMP cytoplasmic domain in imprinting spatial memory for podosome reformation via assembly in membrane islets.
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CITATION STYLE
APA
Gucciardo, E., Mobashir, M., & Lehti, K. (2016). Proactive for invasion: Reuse of matrix metalloproteinase for structural memory. Journal of Cell Biology, 213(1), 11–13. https://doi.org/10.1083/jcb.201603066
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