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Biological properties of Shigella flexneri 2A toxin and its serological relationship to Shigella dysenteriae 1 toxin

Infection and Immunity (1977) 15(3) 796-798
DOI: 10.1128/iai.15.3.796-798.1977
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Abstract

A toxin extracted from heat-inactivated, alkaline-treated Shigella flexneri 2a showed biological properties similar to those of Shigella dysenteriae 1 toxin. The S. flexneri 2a toxin was lethal to mice, enterotoxic for ileal loops of rabbits, and cytotoxic for HeLa cells. A serological relationship between S. flexneri 2a and S. dysenteriae 1 toxin was shown with cross neutralization tests.

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APA

O’brien, A. D., Thompson, M. R., Gemski, P., Doctor, B. P., & Formal, S. B. (1977). Biological properties of Shigella flexneri 2A toxin and its serological relationship to Shigella dysenteriae 1 toxin. Infection and Immunity, 15(3), 796–798. https://doi.org/10.1128/iai.15.3.796-798.1977

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