Cardiovascular health disparities in racial and other underrepresented groups: Initial results from the all of us research program

Abstract

BACKGROUND: All of Us is a novel research program that aims to accelerate research in populations traditionally underrepre-sented in biomedical research. Our objective was to evaluate the burden of cardiovascular disease (CVD) in broadly defined underrepresented groups. METHODS AND RESULTS: We evaluated the latest data release of All of Us. We conducted a cross-sectional analysis combin-ing survey and electronic health record data to estimate the prevalence of CVD upon enrollment in underrepresented groups defined by race, ethnicity, age (>75 years), disability (not able to carry out everyday physical activities), sexual orientation and gender identity lesbian, gay, bisexual, transgender, queer, intersex, and asexual (LGBTQIA+), income (annual household income 75 years (OR, 1.90; 95% CI, 1.81–1.99), disability (OR, 1.60; 95% CI, 1.53–1.68), and income