Personalized computation of fractional flow reserve in case of two consecutive stenoses

Abstract

This paper addresses the problem of personalized computation of fractional flow reserve (FFR). FFR is considered to be the golden standard for making decision on surgical treatment of coronary vessels with multiple stenoses. Computer simulations could simplify the process by non-invasive estimation of FFR based on one-dimensional blood flow model. In this work a problem of two consecutive stenoses is studied. It is shown that in some cases only one of the stenoses has to be to removed, while the other one is insignificant. The structure of vessels is based on patient CT scans. An emphasis is made on the boundary conditions in bifurcation points of the vessels.