Determinants of Effect of Extracorporeal CO 2 Removal in Hypoxemic Respiratory Failure

  • Dianti J
  • McNamee J
  • Slutsky A
  • et al.
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Abstract

Extracorporeal CO2 Removal in Respiratory FailureHeterogeneity among patients with a single diagnosis can mean that the headline result of a trial may obscure harms and benefits among subgroups. This study reports a retrospective analysis of a trial of extracorporeal carbon dioxide removal in respiratory failure testing for physiological determinants of the overall treatment effect.

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Dianti, J., McNamee, J. J., Slutsky, A. S., Fan, E., Ferguson, N. D., McAuley, D. F., & Goligher, E. C. (2023). Determinants of Effect of Extracorporeal CO 2 Removal in Hypoxemic Respiratory Failure. NEJM Evidence, 2(5). https://doi.org/10.1056/evidoa2200295

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