Evaluation of Pcv and Hemoglobin Variations among Malaria Positive and Malaria Negative Patients, At the Ecwa Community Health Centre Bukuru, Jos. Nigeria.

Abstract

Malaria is predominantly caused by plasmodium falciparum parasite. It is a major cause of mortality and morbidity in patients. It causes the excessive destruction of red blood cells during the parasites life cycle. Anemia is a predominant symptom of malaria patient. It is a hematological disorder caused by a de crease in the production of red blood cells, a bone marrow failure or by an increased destruction of red cells. This is because there is decreased erythropoiesis due to the malarial infection. There is the parasitization of red cells by the malaria parasit e which leads to shortened survival or death of erythrocytes. Because of this destruction, packed cell volume and hemoglobin values are reduced when measured in malaria positive patients. This study was conducted among the malaria and non malaria of The EC WA Community Health Centre, Bukuru, Jos in Nigeria. Samples were obtained from malaria positive and malaria negative patients. Their packed cell volume and hemoglobin values were calculated. Result showed a significant difference in the packed cell volume values of the patients. Conclusively, there was a decrease in packed cell volume in malaria patients which seems to be due to the excessive destruction of red cells by malaria parasite.