The oligoribonuclease gene in Streptomyces coelicolor is not transcriptionally or translationally coupled to adpA, a key bldA target

Abstract

Transcriptional analysis of the gene in Streptomyces coelicolor encoding oligoribonuclease indicates that it is not transcriptionally or translationally coupled to adpA, a key bldA target for morphological differentiation. Interestingly, construction and phenotypic analysis of an S. coelicolor oligoribonuclease null mutant revealed a conditional defect in morphological differentiation that is reminiscent of bldA and other known developmental mutants. © 2008 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved.