Comparative Study on Antioxidant Activity and Cytotoxicity of Defatted Kernels of Mango ( Mangifera indica) and Wild Mango ( Irvingia gabonensis and Irvingia wombolu)

Abstract

Defatted kernel powder of mango (Mangifera indica) and wild mango (Irvingia gabonensis and Irvingia wombolu) were analyzed for their in-vitro antioxidant activity and cytotoxicity. Dry matter content of the three kernel types were in the range of 93 to 95%. On defatting, the percentage oil yield of the Irvingia varieties were similar and 200% higher than that of Mangifera indica. The antioxidant activity using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) technique showed that the two Irvingia varieties (DIGK and DIWK) had similar IC50 (p>0.05) but significantly higher than that of Mangifera indica kernel (DMIK) (p<0.05). Likewise, results from the Ferric Reducing Antioxidant Power (FRAP) technique and Cytotoxicity assay confirmed the higher potency of DMIK over the Irvingia kernels.