Fatal Fungicide-Associated Triazole-Resistant Aspergillus fumigatus Infection, Pennsylvania, USA

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Abstract

We report a fatal infection in a 65-year-old immunocompromised male patient caused by pan-triazole–resistant Aspergillus fumigatus containing a TR34/L98H genetic mutation linked to agricultural fungicide use. Clinical and environmental surveillance of triazole-resistant A. fumigatus is needed in the United States to prevent spread and guide healthcare and agricultural practices.

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Bradley, K., Le-Mahajan, A., Morris, B., Peritz, T., Chiller, T., Forsberg, K., … Gould, J. M. (2022). Fatal Fungicide-Associated Triazole-Resistant Aspergillus fumigatus Infection, Pennsylvania, USA. Emerging Infectious Diseases, 28(9), 1904–1905. https://doi.org/10.3201/eid2809.220517

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