Abstract
Using different prebiotically plausible activating reagents, the RNA ligation yield was significantly increased in the presence of Mn(ii). The mechanism of the activation reaction has been investigated using 5′-AMP as an analogue.
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CITATION STYLE
APA
Liu, Z., Jiang, C. Z., Bond, A. D., Tosca, N. J., & Sutherland, J. D. (2024). Manganese(ii) promotes prebiotically plausible non-enzymatic RNA ligation reactions. Chemical Communications, 60(51), 6528–6531. https://doi.org/10.1039/d4cc01086h
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