Pechmann reaction promoted by boron trifluoride dihydrate

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Abstract

The Pechmann reaction of substituted phenols 1a-e with methyl acetoacetate (2) can be activated by boron trifluoride dihydrate (3) to give the corresponding 4-methylcoumarin derivatives 4a-e in excellent yield (98-99 %). © 2005 by MDPI.

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APA

Stoyanov, E. V., & Mezger, J. (2005). Pechmann reaction promoted by boron trifluoride dihydrate. Molecules, 10(7), 762–766. https://doi.org/10.3390/10070762

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