Effects of biological and mineral compounds in aflatoxin-contaminated diets on blood parameters and immune response of broiler chickens

Abstract

Four hundred broiler chicks were allocated to eight treatments and five replicates in a completely randomized design for 7-42 days. Treatments included basal diet (NC), NC + 1 mg/kg aflatoxin (PC), PC + 1 kg/ton Toxeat¯ (a toxin binder), PC + Lactobacillus strains (L), PC + Bacillus subtilis JQ618 strain (B), PC + Saccharomyces cerevisiae’s cell wall (Y), PC + B + L + Y (BLY) and PC + hydrated sodium calcium aluminosilicate (HA). At 28 days of age, glucose and total protein serum concentrations in PC group were lower than other treatments (p > .05), but in toxin binder receiving treatments were in the middle of NC and PC groups. At 35 days of age, 48 h after dinitrochlorobenzene injection Y showed more skin swelling (p > .05) and 24 h after injection, the aluminosilicate showed a poor performance with for phytohemagglutinin response. At 35 days, IgG titre and serum cholesterol concentration had a similar process to sheep red blood cell (SRBC) and no significant differences were recorded between aflatoxin inhibitor receiving treatments (p > .05). SRBC, IgG, IgM titres and serum cholesterol concentration at 28 days and IgM titres at 35 days were not affected by treatments (p > .05). It can be concluded that a prebiotics and probiotics mixture such as BLY is suitable for improving immune function and serum biochemical parameters as an effect of feeding aflatoxin-contaminated diet.