Reversing CD8+ T-cell exhaustion with DLI

Abstract

In this issue of Blood, Bachireddy et al explain why infusion of donor CD4 T cells induces remission in some patients with persistent chronic myeloid leukemia (CML) after allogeneic hematopoietic cell transplantation (HCT), but not in others.1 (Figure Presented) © 2014 by The American Society of Hematology.