The Effect of Radiological and Laboratory Parameters on Prognosis in COVID 19 Disease

Abstract

INTRODUCTION: A previously unknown contagious disease, which later turned out to be a worldwide pandemic originated from Wuhan, capital of Hubei province in China by the end of 2019. While this upheaval affected numerous countries tragically, mortality rate and necessity for ICU were relatively low in Turkey. METHODS: A total of 166 patients (65 at ICU, 101 at pandemic service) were analyzed to uncover effect of radiological and laboratory parameters on prognosis in COVID-19. One hundred and one patients (60.8%) were treated in pandemic service and 65 (39.15%) were treated in ICU. RESULTS: Mean age of the patients in pandemic service was 61.1±16.2 (23-93) and of patients in ICU was 64.6±15.7 (15-90) (p>0.05). Initial mean CRP value for pandemic service group was 68.14±6.5 mg/dL (3.11-271), whereas it was 117.07±11.5 mg/dL (0-360) for ICU (p<0.05). Mean D-dimer value for the patients in ICU was 5572.2±1075.6 ng/mL and for the patients in pandemic service it was 1904.9±290.7 ng/mL (p<0.05). There was a correlation between CRP and D-dimer values (p<0.05). Of 66 patients in ICU group, 30(49.2%) had early stage CT findings, 22 (36.1%) had progressing stage CT findings and 9 (14.8%) had severe stage CT findings. However, of 101 patients in pandemic service group, 67 (66.9%) had early stage CT findings, 32 (31.7%) had progressing stage CT findings and 2 (2%) had severe stage CT findings. DISCUSSION AND CONCLUSION: CT staging is a substantial prognostic factor and may help clinicians decide treatment modality. Furthermore, CRP and D-dimer values are also prognostic during follow-up. Thus, the necessity of taking these parameters into consideration while implementing treatment algorithms has emerged. As a conclusion, CT stage, CRP and D-Dimer values should be adopted as crucial prognostic factors in order to provide efficient healthcare.