3-Amino-N-benzyl-6-(4-fluorophenyl)thieno[2,3-b]pyridine-2-carboxamide

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Abstract

In the title compound, C21H16FN3OS, the thieno[2,3-b]pyridine system forms dihedral angles of 10.57 (12) and 83.87 (5)°with the fluorophenyl ring at the 6-position and the phenyl ring of the benzyl group, respectively. In the crystal, molecules are linked by weak N - H⋯N anf N - H⋯O hydrogen bonds and π-π stacking interactions involving fluorophenyl rings of adjacent molecules, with a centroid-centroid distance of 3.648 (10) Å. In addition, intramolecular N - H⋯S and N - H⋯O hydrogen bonds contribute to the stability of the molecular conformation.

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Zhao, J. N., Yang, S. Y., & Yang, L. (2012). 3-Amino-N-benzyl-6-(4-fluorophenyl)thieno[2,3-b]pyridine-2-carboxamide. Acta Crystallographica Section E: Structure Reports Online, 68(6). https://doi.org/10.1107/S160053681202212X

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