Highly Sensitive Cardiac Troponin T as a Biomarker of Myocardial Injury in Acyanotic Congenital Heart Disease

Abstract

An observational cross sectional study was conducted at a tertiary care center over a period of one year (April 2017 to March 2018). Stable children with ACHD aged between 6 months to 5 years were selected as cases and age matched children without ACHD as controls. Echocardiography was done in all the patients with clinical findings of ACHD. A total of 83 children (55 cases and 28 controls) were enrolled. The severity of the ACHD was determined by the defect size and the pressure gradient across the defect on echocardiography. Levels of hs-cTnT were measured using electrochemiluminesence assay. These levels were co-related with the defect size and the pressure gradient.