HIF1a or HIF2a: Enhancing CD8þ t-cell fitness for antitumor immunity

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Abstract

Adoptive T-cell therapy requires the transferred lymphocytes to adapt to the hypoxic tumor microenvironment. In this issue, Veli¸ca and colleagues found that modified HIF2a expression in CD8þ T cells increases antitumor efficacy.

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CITATION STYLE

APA

Chen, J. (2021). HIF1a or HIF2a: Enhancing CD8þ t-cell fitness for antitumor immunity. Cancer Immunology Research, 9(4), 364. https://doi.org/10.1158/2326-6066.CIR-21-0114

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