Hybrid models of cell and tissue dynamics in tumor growth

Abstract

Hybrid models of tumor growth, in which some regions are de- scribed at the cell level and others at the continuum level, provide a exible description that allows alterations of cell-level properties and detailed descrip- tions of the interaction with the tumor environment, yet retain the computa- tional advantages of continuum models where appropriate. We review aspects of the general approach and discuss applications to breast cancer and glioblas- toma.