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Increased glyoxalase-1 levels in fkbp5 knockout mice caused by glyoxalase-1 gene duplication

G3: Genes, Genomes, Genetics (2013) 3(8) 1311-1313
DOI: 10.1534/g3.113.006445
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Abstract

Fkbp5 is genetically linked to stress-related diseases. Fkbp5 knockout mice are available and widely used to explore the role of Fkbp5 in health and disease. We found that these mice carry a gene duplication of glyoxylase-1, which explains why glyoxylase-1 levels are increased in the Fkbp5 knockout mice. © 2013 Kollmannsberger et al.

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Kollmannsberger, L. K., Gassen, N. C., Bultmann, A., Hartmann, J., Weber, P., Schmidt, M. V., & Rein, T. (2013). Increased glyoxalase-1 levels in fkbp5 knockout mice caused by glyoxalase-1 gene duplication. G3: Genes, Genomes, Genetics, 3(8), 1311–1313. https://doi.org/10.1534/g3.113.006445

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