Glomerular Deposition of Properdin in Henoch-schonlein Syndrome and Idiopathic Focal Nephritis

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Abstract

Biopsy of renal tissue from four patients with idiopathic focal nephritis and three patients with Henoch-Schönlein syndrome showed that C3 and properdin were deposited with IgA in the glomerular mesangium, Clq could not be detected. These observations suggest that glomerular injury in disorders characterized by mesangial deposits of IgA and C3 is mediated via the properdin system. © 1973, British Medical Journal Publishing Group. All rights reserved.

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Evans, D. J., Williams, D. G., Peters, D. K., Sissons, J. G. P., Boulton-Jones, J. M., Ogg, C. S., … Hoffbrand, B. I. (1973). Glomerular Deposition of Properdin in Henoch-schonlein Syndrome and Idiopathic Focal Nephritis. British Medical Journal, 3(5875), 326–328. https://doi.org/10.1136/bmj.3.5875.326

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