Microwave-assisted ammonium formate-mediated synthesis of Hantzsch dihydropyridines under solvent-free conditions - A green protocol

Abstract

Microwave-assisted ammonium formate-mediated eco-friendly synthesis of structurally varied Hantzsch dihydropyridines under solvent-free conditions has been successfully accomplished with good yield, minimization of toxic reagents and organic solvents in the process. The elimination of the inorganic support decreased the disposal problem and the extremely small reaction time minimized energy dissipation.