Plasma DNA and metastatic castration-resistant prostate cancer: The odyssey to a clinical biomarker test

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Abstract

Comprehensive plasma DNA analysis identifies clinically actionable genomic aberrations. Cancers harboring disruption of TP53 or BRCA2 or ATM detected in plasma have significantly worse outcomes on novel AR targeting.

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Jayaram, A., Wetterskog, D., & Attard, G. (2018). Plasma DNA and metastatic castration-resistant prostate cancer: The odyssey to a clinical biomarker test. Cancer Discovery, 8(4), 392–394. https://doi.org/10.1158/2159-8290.CD-18-0124

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