Seasonal changes in testicular contents of testosterone and androstenedione and in the metabolic clearance rate of testosterone in the sand rat (Psammomys obesus)

Abstract

Adult male sand rats (Psammomys obesus) were caught in the Beni-Abbes area. The highest testicular contents of androgens (ng/testis) were observed in autumn and in winter (testosterone: 7.6 ± 1.1; androstenedione: 0.76 ± 0.11) and the lowest in early summer (June) (testosterone: 1.5 ± 0.3; androstenedione: 0.20 ± 0.05). Values had increased by late July. Annual variations of the testosterone metabolic clearance rate (litres/24 h/100 g body wt) were similar to those of testicular androgens; values were high in winter (6.7 ± 0.7) and lowest in June (3.2 ± 0.3). The onset of testicular endocrine activity in sand rats was concomitant both with the highest temperatures and the start of reduction in photoperiod; its regression occurred when temperature and photoperiod were increasing.