Anticonvulsant and sedative effects of Salvadora persica L. stem extracts

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Abstract

The effect of Salvadora persica L. stem extracts on the potentiation of sodium pentobarbital activity and on generalized tonic-clonic seizure produced by pentylenetetrazol (PTZ) on the rat is reported. The extracts of Salvadora persica L. extended sleeping-time and decreased induction-time induced by sodium pentobarbital; in addition it showed protection against pentylenetetrazol-induced convulsion by increasing the latency period and diminishing the death rate. Copyright © 2002 John Wiley & Sons, Ltd.

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Monforte, M. T., Trovato, A., Rossitto, A., Forestieri, A. M., D’Aquino, A., Miceli, N., & Galati, E. M. (2002). Anticonvulsant and sedative effects of Salvadora persica L. stem extracts. Phytotherapy Research, 16(4), 395–397. https://doi.org/10.1002/ptr.977

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