Guidelines for lupus anticoagulant testing in South Africa

  • Bailly J
  • Louw S
  • De Koker A
  • et al.
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Abstract

The antiphospholipid syndrome (APS) is a thrombophilic condition characterised by thromboses and/or adverse pregnancy outcomes. International criteria for the diagnosis of APS require that certain laboratory and clinical criteria are met. Lupus anticoagulant (LA) testing using coagulation tests is an essential component. This review aims to provide a national guideline for LA testing in the South African context and intends to standardise testing, interpretation and reporting of results. Key aspects of the pre-analytical, analytical and post-analytical phases of testing are considered and highlighted.

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Bailly, J., Louw, S. (Susan), De Koker, A. (Annemarie), Potgieter, J. J. C., Coetzee, M. J., Chapanduka, Z. C. (Zivanai C., & Opie, J. J. (2020). Guidelines for lupus anticoagulant testing in South Africa. The Journal of Medical Laboratory Science and Technology of South Africa, 2(1), 6–12. https://doi.org/10.36303/jmlstsa.2020.2.1.39

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