Concise review: Periodontal tissue regeneration using pericardium membrane as guided bone regeneration.

Abstract

Bone damage is one of the problems caused by periodontal disease and can be repaired through regenerative periodontal therapy. The objective of regenerative periodontal treatment is to reestablish the tooth supporting tissue that has been lost because of inflammatory periodontal disease by making arrangement of periodontal ligament, new cementum and alveolar bone. Be that as it may, an effective regeneration of periodontal tissues is difficult to accomplish generally because of development of a long junctional epithelium and less predictable periodontal regeneration. One of the techniques to ease the regeneration process is using guided bone regeneration (GBR). GBR working as a physical barrier between tissues with differential rate of regeneration, so as to avert the movement of both gingival and epithelial connective tissue cells along the root surface. GBR allowing hard tissues like alveolar bone to have time and space to regenerate, so bone formation can occur. Pericardium membrane is one of the barrier membranes for guided bone regeneration. These membranes have a few properties in selection of a suitable for guided tissue regeneration which includes biocompatibility, biodegradation, immunogenicity. Pericardium membrane mostly contain type I collagen, an important protein involved in several process in tissue formation. Pericardium membrane also is a resorbable material that offers convenience with one step surgery without additional surgery to remove it. Several studies showed that the use of pericardium membrane as GBR can significantly improve the bone formation. Hence, Pericardium membrane could be a suitable material as GBR for periodontal tissue regeneration.