A Review on Chalcones Synthesis and their Biological Activity

Abstract

Chalcones are a valuable molecule of medicinal importance due to presence of reactive ketoethylenic group –CO–CH=CH–, belonging to the flavonoid family. These reactive α,β-unsatutated keto function in chalcones are  responsible for their biological activity. Chalcone can be synthesized by several methods using aldehydes and ketones as starting material. This review is focused about different methods of synthesis and versatile biological activity of chalcones including antimicrobial, anticancer, antioxidant, antimalarial, antituberculosis etc.