Patterns of Ethambutol Ocular Toxicity in Extended Use Therapy

Abstract

We report the clinical and perimetric findings of three patients with ethambutol toxicity with an extended use regimen. In this observational case series, we extracted data from case records that included age, sex, complaints, details of the current disease, anti-tubercular therapy, ocular findings, and perimetric findings. We identified three patients, two female and one male with ages ranging from 16 to 65 years (mean: 37 years). The perimetric patterns we observed were incomplete homonymous hemianopia in two patients and bitemporal hemianopia in one. Incomplete hemianopia was the predominant perimetric finding, suggesting that the likely lesions were chiasmal or post-chiasmal rather than pre-chiasmal.