Electrophilic Sulfoximidations of Thiols by Hypervalent Iodine Reagents

Abstract

A new electrophilic sulfoximidation of thiols has been developed. Using sodium hydride as a base, the treatment of sulfoximidoyl-containing hypervalent iodine(III) reagents with thiols affords the corresponding N-ulfenylsulfoximines (N-thiosulfoximines) in good to excellent yields. A plausible mechanism is proposed.