An efficient rhodium-catalyzed double hydroaminocarbonylation of alkynes with carbon monoxide and amines affording 1,4-diamide derivatives

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Abstract

The hydroaminocarbonylation of terminal alkynes with carbon monoxide and pyrrolidine or piperidine catalyzed by rhodium complexes affords 1,4-diamide derivatives in good to high yields. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

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Huang, Q., & Hua, R. (2007). An efficient rhodium-catalyzed double hydroaminocarbonylation of alkynes with carbon monoxide and amines affording 1,4-diamide derivatives. Advanced Synthesis and Catalysis, 349(6), 849–852. https://doi.org/10.1002/adsc.200600466

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