Microbiology Select

Abstract

This issue's Microbiology Select describes recent insights into the mechanisms and consequences of viral infections, including a functional genomics screen that reports an array of previously unknown host factors required for HIV-1 infection of cultured human cells. New work also defines host factors that restrain the release of HIV-1 from cells and reveals how a class of antimicrobial peptides inhibits adenoviral infections. Other discoveries include a protein in mitochondria that modulates antiviral signaling, and evidence that a rare but dangerous form of skin cancer may have a viral origin.