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Role in vivo for gamma interferon in control of pneumonia caused by Chlamydia trachomatis in mice

Infection and Immunity (1988) 56(11) 3004-3006
DOI: 10.1128/iai.56.11.3004-3006.1988
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Abstract

In a model of pneumonia caused by murine Chlamydia trachomatis, depletion experiments with monoclonal antibody to gamma interferon (IFN-γ) made mice more susceptible. Repletion experiments giving exogenous recombinant murine IFN-γ were not consistently protective. IFN-γ may be necessary but not sufficient in host defense against the organism.

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Williams, D. M., Byrne, G. I., Grubbs, B., Marshal, T. J., & Schachter, J. (1988). Role in vivo for gamma interferon in control of pneumonia caused by Chlamydia trachomatis in mice. Infection and Immunity, 56(11), 3004–3006. https://doi.org/10.1128/iai.56.11.3004-3006.1988

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