Morphological parameters of blood of calves with cryptosporidiosis after applying different treatment regimens

Abstract

Recently the livestock farmers of Baltasinsky, Kukmorsky, Sabinsky, Alkeevsky and other regions of the Republic of Tatarstan have increasingly frequently faced the young cattle diseases associated with pathology of the gastrointestinal tract that have not been treated by the classical scheme of diseases with diarrhea symptoms.Sick calves had acute and subacute catarrhal gastroenteritis mainly in the later stages of which accompanied by the inflammatory process in the posterior segment of the small intestine. The manifestations of structural changes in the subepithelial lymphoid tissue of the intestine, in the stagnant digestive glands and regional lymph nodes were increased with a severity level of the clinical symptoms of the disease.In this regard, in order to obtain a complete picture of the effect of cryptosporidiosis invasion on the peripheral blood condition of sick calves, hematological studies were conducted in the dynamics of the development of the infectious process. We have studied the content of red blood cells, white blood cells including lymphocytes, granulocytes, as well as monocytes and hemoglobin on the 7th, 14th and 30th days of the experiment. Hematological studies of calves infected with spontaneous invasion of cryptosporidiosis, and after treatment, had been carried out in 2016 – 2018 at the OJSC “KukmorAgroChimService” in the Kukmorsky district of the Republic of Tatarstan in the Russian federation. Cryptosporidiosis clinically insane calves had erythropenia and leukocytopenia in the blood and low hemoglobin. Reduced oxygen capacity of the blood contributed to the development of the secondary destructive changes in the organs of hematopoietic organs. The established dynamics of a decrease in the content of eosinophilic granulocytes in the blood of calves in the first and especially in the second groups indicated a high therapeutic effect of the drugs used. Starting from the 7th day, due to the therapeutic effect of the tested medications in the places of the pathogenic effects of cryptosporidia, regenerative processes were intensified. It affected the morphological parameters of the blood.