Effect Of Hyperlipidemia On Nerve Conduction Velocity In Type II Diabetes Mellitus

Abstract

Objectives: The pathogenesis of neuropathy in type II Diabetes Mellitus is multifactorial. Hyperlipidemia may contribute to the development of diabetic neuropathy. This study aimed to assess the correlation between hyperlipidemia and diabetic neuropathy. Material And Method: The study included 60 known cases of Type II diabetes mellitus attending diabetic OPD at GMCH, Aurangabad of age 30-60 years with duration of 5-10 years. The cases were divided into two groups; Group I included diabetic patients with normolipidemia and Group II included diabetic patients with hyperlipidemia. Biochemical investigations included HbA1c, total cholesterol and triglycerides. Nerve conduction velocity was done by computerized Micromed RMSEMG system.Statistical analysis was done by unpaired student's t test. Results: The study revealed significant reduction in conduction velocity in diabetic patients with hyperlipidemia.