Nanobiodevice-based single cell analysis and single biomolecule analysis

Abstract

A nanobiodevice is a piece of contrivance, equipment, machine, or component, which is created by overlapping multidisciplinary activities associated with nanotechnology and biotechnology, intended for biological, medical, and clinical purposes. We developed nanobiodevices for biomedical applications, including single cancer-cell diagnosis for cancer metastasis, circulating tumor cell CTC. detection by microfluidic devices, nanopillar devices for the ultrafast analysis of genomic DNA and microRNA, nanopore devices for single DNA and microRNA sequencing, nanowire devices for exosome analysis, single-molecular epigenetic analysis, quantum switching in vivo imaging of iPS cells and stem cells, and quantum technology-based cancer theranostics.