Chemical composition, enantiomeric distribution and AChE-BChE activities of the essential oil of Myrteola phylicoides (Benth) Landrum from Ecuador

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Abstract

The volatile constituents of the essential oil (EO) of Myrteola phylicoides (Benth) Landrum, from Ecuador, extracted by steam distillation have been analyzed. A total of 37 compounds, representing 90.30% the total essential oil sample were identified. Monoterpenes hydrocarbons (53.06%) and sesquiterpene hydrocarbons (35.24%) were the principal groups of compounds. The major components were identified as α-pinene (30.94%), (E)-caryophyllene (21.93%), β-pinene (14.45%) and α-humulene (9.56%). The essential oil of M. phylicoides showed weak in vitro activity against AChE inhibition with IC50 value 60.8 μg/mL and a low BChE activity with IC50 value >250 μg/mL. This is the first report on the chemical composition of the essential oil of this species.

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Calva, J., Castillo, J. M., Bec, N., Ramírez, J., Andrade, J. M., Larroque, C., & Armijos, C. (2019). Chemical composition, enantiomeric distribution and AChE-BChE activities of the essential oil of Myrteola phylicoides (Benth) Landrum from Ecuador. Records of Natural Products, 13(4), 355–362. https://doi.org/10.25135/rnp.112.18.09.893

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