Differences in Botulinum Toxin Injection Into Temporal Muscles in Sleep Bruxism and Chronic Migraine

Abstract

Botulinum toxin (BoNT), a potent neurotoxin that reversibly blocks presynaptic acetylcholine release, has been used successfully to treat sleep bruxism (SB) and chronic migraine (CM). However, studies investigating injection protocols such as drug dosage and injection site in the temporal muscle (TM) have rarely been reviewed. Therefore, recent studies involving the application of BoNT to the TM in patients with SB and CM was reviewed in this study.