Nitrogen-Doped Graphene Aerogel for Simultaneous Detection of Dopamine and Ascorbic Acid in Artificial Cerebrospinal Fluid

Abstract

Detection of biological relevant analytes using inexpensive and affordable sensors is of high importance for further development of personalized healthcare. Combining electrochemistry with sensing platforms based on new emerging nanomaterials is of immense interest within the scientific community because such connection could bring amelioration in term of sensitivity and possible miniaturization to traditional sensors. Herein, nitrogen-doped graphene aerogel (N-GA) was utilized for detection of biologically important analytes, dopamine and ascorbic acid. Both analytes revealed good linear relationship between current peaks and concentration with detection limit of 0.06 and 0.08 μ M for dopamine and ascorbic acid, respectively. Moreover, N-GA was also applied for simultaneous detection of dopamine along with ascorbic acid in artificial cerebrospinal fluid. In this case, the limit of detection for dopamine reached value of 0.42 μ M.