P578 Therapy refractory ulcerative colitis patients may benefit from appendectomy: long-term clinical results from a multicentre prospective cohort series

Abstract

Aim: Appendicectomy may reduce relapses and need for medication in ulcerative colitis (UC) patients, however, long-term prospective data are lacking. We aim to analyse the effect of appendicectomy on therapy refractory UC. Method(s): In this prospective cohort series, all consecutive refractory UC patients referred for proctocolectomy between November 2012 and June 2015 were counseled to undergo appendicectomy instead. Primary endpoint was clinical response (decrease of >=3 points of partial Mayo ranging from 0-9) at long-term follow-up. Secondary endpoints were endoscopic remission (endoscopic Mayo score