Metal complexes of dithiocarbamate derivatives and its biological activity

Abstract

The recent applications of various substituted metal complexes of dithiocarbamate derivatives based drugs and have clearly shown that the biological approaches for this new generation of dithiocarbamate would be a symbol of implementing and development of better medical agents socially. In this brief review, the synthesis and biological activities of dithiocarbamate complexes are discussed. Dithiocarbamate is known to contain (R2NCS2-or RNHCS2-) containing fragments act simply as counter ions. The dithiocarbamate group (Rdtc-) of ligands has been discovered to perform usually as uninegative bidentate ligands coordination via each of sulfur atoms with many metal ions. The metal complexes with these ligands have been extensively investigated and are of interest in many fields such as flotation agents and as antifungal agents. Due to the chelating feature they are utilized as scavengers in water-waste processing.