3,4-Dihydroxycinnamic acid attenuates the fatigue and improves exercise tolerance in rats

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Abstract

3,4-Dihydroxycinnamic acid (3,4-DA) is a natural compound with high antioxidant potential found in various foods. This study found that animals administered with 3,4-DA had higher exercise tolerance, reduced blood lactate, and markers of hepatic oxidation. Blood glucose and antioxidant enzymes were not affected by this treatment. 3,4-DA may have applicability in reducing the fatigue associated with exercise.

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Novaes, R. D., Gonçalves, R. V., Do Carmo G. Peluzio, M., Natali, A. J., & Maldonado, I. R. S. C. (2012). 3,4-Dihydroxycinnamic acid attenuates the fatigue and improves exercise tolerance in rats. Bioscience, Biotechnology and Biochemistry, 76(5), 1025–1027. https://doi.org/10.1271/bbb.111006

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