Tuberculosis post-liver transplantation: A rare but complicated disease

Abstract

Introduction: Tuberculosis is a rare but serious complication after transplantation. We report a case and discuss its presentation and management. Clinical Picture: A 60-year-old Indonesian male presented initially with fever, acute confusion and rapidly progressive right upper lobe pneumonia 3.5 months post-liver transplant, and was diagnosed with pulmonary tuberculosis by positive sputum smear for acid-fast bacilli and tuberculosis culture. Treatment/Outcome: Standard anti-tuberculosis therapy was administered but was complicated by interaction with cyclosporine and drug-induced cholestasis. Conclusion: A high level of suspicion, prompt anti-tuberculosis treatment and close follow-up are essential in management of post-transplant tuberculosis.