Performance of stool-based Xpert MTB/RIF assay in the diagnosis of presumptive pulmonary tuberculosis in adults unable to expectorate sputum

Abstract

This study aimed to assess the value of the Xpert MTB/RIF assay (Xpert) for diagnosing PTB using stool samples from adults in low HIV prevalence settings. Although the diagnostic yield of Xpert on stool samples is inferior to that of Xpert on RTS, stool-based Xpert may be useful in diagnosing patients with presumptive PTB who cannot expectorate sputum and do not opt for BALF collection.