Tingkat kepatuhan pasien HIV/AIDS terhadap penggunaan obat anti retroviral (ARV) di RSUD Gunung Jati Cirebon

Abstract

Background: Acquired Immune Deficiency Syndrome (AIDS) is a syndrome or symptoms with severe immune deficiency as a late-stage manifestation. Antiretroviral (ARV) is a drug that can suppress the development of HIV in the body. Some ARVs commonly used in Indonesia include Lamivudin and Zidovudin. Adherence to antiretroviral treatment has been recognized as an essential component for achieving an optimal therapeutic program. Objective: This study aimed to determine the characteristics of patients, treatment characteristics, adherence levels, and factors that affect the level of adherence of HIV/AIDS patients (patient characteristics and types of antiretroviral therapy) at Seroja Clinic RSUD Gunung Jati Cirebon. Method: The study involved 75 patients, using the Morisky Modified Scale (MMS) questionnaire. Result: The results obtained were descriptive analysis for patient characteristic data, treatment characteristics, patient adherence level, and Chi square statistical test to identify the correlation between patient's individual factors and adherence level. The results of the research showed that 56% of the patients were male, 64% of them aged 31-40 years, 50.67% went to SMA (high school) as their highest education attainment, and 60% took private jobs. The most treatment characteristic was the combination of Tenofovir + Lamivudin + Efavirenz at 45.3%. The adherence level of HIV/AIDS patients in Seroja Clinic of RSUD Gunung Jati Cirebon was currently 34.7% (moderate) and low (21.3%). Conclusion: The Chi Square Test results showed that there was no correlation between such patient characteristics as age, sex, education level, occupation, and types of antiretroviral therapy and HIV/AIDS patient adherence.