Self-expandable duodenal metal stent placement for the palliation of gastric outlet obstruction over the past 20 years

Abstract

Introduction Duodenal stent placement is a palliative option for management of malignant gastric outlet obstruction (GOO). In the last 20 years, management of gastrointestinal cancers has considerably changed. It is unknown if these changes have affected clinical outcome of duodenal stent placement. Methods Retrospective cohort study conducted in a tertiary referral center. Patients who underwent duodenal stent placement for GOO-symptoms due to a malignant stricture were included. Primary outcome was GOO-symptom free survival. Secondary outcomes included stent-related adverse event rates. Potential explanatory parameters such as period of stent placement (1998-2009 vs 2010-2019), prior treatments, peritoneal deposits, and stricture length were evaluated using multivariable Cox regression analysis. Results A total of 147 patients (62â Š% male; median age 64 years) were included. After a median of 28 days after stent placement, 82 patients (57â Š%) had recurrent GOO-symptoms. GOO-symptom free survival was significantly lower in 2010-2019 (Pâ Š