Versatile supramolecular copper(II) Complexes for Henry and Aza-Henry reactions

Abstract

Chiral supramolecular metal-organic frameworks assembled from copper complexes catalyse Henry and aza-Henry reactions of aromatic and aliphatic aldehydes and N-protected aromatic imines in high yield and good to excellent enantioselectivity. Reactions can be performed in the absence of base in ethanol or water. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.