IDENTIFICATION OF BIOACTIVE PRINCIPLES OF AVICENNIA OFFICINALIS FRUIT EXTRACT IN METHANOL AND SCREENING FOR ANTIBACTERIAL ACTIVITY

Abstract

Avicennia officinalis (AO) belongs to family Avicenniaceae. It finds a prominent place in folk medicine. Hence the present work was carried out for the identification of bioactive principles in the fruits of Avicennia officinalis and screened for the antibacterial activity against selected test cultures. The methanolic extracts has high efficacy against the test cultures. The methanolic extracts were further purified by column chromatography. With the aid of 1H NMR, 13C NMR and GC-MS analysis. The structure of the compounds were detected as Phenols namely 1, 2, 3 Benzene triol and 4, 4’-(1-methylethyldiene)bis2-methyl and both the compounds exhibited antibacterial activity. This report of ours is the first one regarding the 1, 2, 3 Benzene triol and 4, 4’-(1-methylethyldiene) bis 2-methyl in the plant Avicennia officinalis.